怀孕快三个月这两天突然腰痛

Towards a ‘super-vaccine’ for swine bacterial diseases Among the most serious diseases in pigs are those that are caused by bacteria that live in their throats, airways or tonsils and can cause severe lung infections such as pneumonia. Infected animals either die quickly or fail to grow normally, resulting in substantial economic costs to the worldwide pig industry and adding to food security concerns. Because the infections are difficult to diagnose, and current vaccines have limited efficacy, antibiotics are now in widespread use in efforts to reduce infection. A new five-year, £5.6 million grant awarded by the Biotechnology and Biological Sciences Research Council (BBSRC) under its strategic longer 怀孕快三个月这两天突然腰痛 and larger grant (LoLa) scheme, which supports research projects requiring ‘big’ science approaches and longer timescales, aims to develop a new vaccine and a diagnostic tool to combat the four most common bacteria that cause infections in pigs. The grant has been awarded to a consortium of researchers at the University of Cambridge, Imperial College London, the London School of Hygiene and Tropical Medicine, and the Royal Veterinary College, as well as Huazhong Agricultural University in China, and involves three UK government-funded agencies. The consortium also receives support from Pfizer Animal Health. ‘This combined expertise has generated a new opportunity that is highly synergistic and where real progress is possible,’ said Professor Maskell, Head of the Department of Veterinary Medicine and leader of the Cambridge component. ‘It’s also a perfect marriage between fundamental biological research and applied clinical outcomes.’ ‘As a first step, we are isolating bacteria from pigs and assembling the largest ever sequenced collection of these types of bacteria,’ explained co-investigator Dr Dan Tucker. ‘From this, we’ll design and assemble appropriate super-vaccines and single-platform diagnostic tests. Crucially, these will immunise and test pigs for all four pathogens at the same time.’ In the final year of the project, field trials will be carried out in China, where dedicated facilities for this type of work are already set up. Commenting on the timeliness of the BBSRC funding, Professor Maskell added: ‘Technical innovations and the availability of genome data have progressed to such an extent, and continue to do so, that only recently has it become possible to embark on this type of programme to find effective vaccines and diagnostics.’ For more information, please contact Professor Duncan Maskell (djm47@cam.ac.uk), Marks

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